Financial Incentives to Support Statin Adherence and Lipid Control (Habit Formation): A Randomized Clinical Trial (12:15 -13:30)

Authors: Iwan Barankay, Peter P. Reese, Mary E. Putt, Louise B. Russell, George Loewenstein, David Pagnotti, Jiali Yan,  Jingsan Zhu, Ryan McGilloway, Troyen Brennan, Darra Finnerty, Karen Hoffer, Sakshum Chadha, Kevin G. Volpp

Abstract:
Importance: Financial incentives can improve medication adherence and CVD risk, but the optimal design to promote sustained adherence after incentives are discontinued is unknown.

Objective: To determine whether 6-month interventions involving different financial incentive designs for statin adherence reduce low-density lipoprotein cholesterol (LDL-C) levels from baseline to 12-months.

Design: Four-arm, randomized trial conducted from August 2013 to July 2018.
Setting: Several large US Insurer or Employer populations and the University of Pennsylvania Health System.

Participants: Random sample of 805 adults with elevated risk of CVD, sub-optimal LDL-C control and evidence of imperfect adherence to their statin medication.